The study reviews 45 of the anti-diabetic plants and their products have shown experimental or clinical anti-diabetic activity.

In preliminary clinical and experimental observations, the dried sap of the al0e plant is a traditional remedy used for diabetes in the Arabian Peninsula. In fact it is one of the many traditional remedies used in diabetes in the Arabian Peninsula. 5 patients wit non-insulin-dependent diabetes and in Swiss albino mice were studied. With one half teaspoon of the aloes ingested daily for 4-14 weeks, the fasting serum glucose level fell in every patient from 273 to 151 with no weight gain or loss. In normal mice, the doses of 10 mg twice daily of glibenclamide and 500 mg twice daily of aloes induce hypoglycaemia (an abnormally low level of sugar) after 5 days. 71 from 91, versus 130 in the control animals only glibenclamide was effective after 3 days. Glibenclamide and aloes noticeably reduced the fasting plasma glucose in the diabetic mice after 3 days. Only the aloes was useful after that and by day number 7, the plasma glucose was 394 versus 64, in the controls and 726 in the glibenclamide treated group. The conclusion to this study was aloes contains a hypoglycaemic agent, which lowers the blood glucose, however the specific cause is unknown.

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